GreeneryBio
Cnidium Monnieri Extract

Cnidium Monnieri Extract

Botanical Name: Cnidium monnieri (L

Chemical identity

CAS Number
484-12-8
Appearance
Brownish-yellow powder Mesh: 80 mesh Specification: 10%-98% Osthole MOQ: 25 kg A
MOQ
1 kg
Lead Time
7-15 business days

Certifications

ISO 9001ISO 22000

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Product Description

Introduction

Cnidium Monnieri Extract is derived from the dried fruits of Cnidium monnieri (L.) Cuss., mainly from high-quality Chinese planting bases, complying with relevant cosmetic and pharmaceutical standards. Adopting advanced low-temperature solvent extraction, membrane separation and spray-drying technology, it maximizes bioactive components while removing impurities and residues[6].

Its key active component is Osthole (10%-98%, HPLC-detected), combined with Bergapten, Xanthotoxin and Isoimperatorin for synergistic efficacy. Core advantages: traceable raw materials, 15% higher extraction rate than industry average, customizable specifications (10:1 to 98% Osthole), and strict quality testing[6].

Key Active Compounds

The extract’s activity comes from coumarin derivatives, with key components as follows:

  • Osthole (CAS No.: 484-12-8): Primary active component, with antibacterial, anti-inflammatory, antipruritic, neuroprotective effects, and can regulate reproductive health and bone metabolism[7].

  • Bergapten: Enhances Osthole’s antibacterial and anti-inflammatory effects, relieves skin irritation and allergies synergistically[8].

  • Xanthotoxin: Strong antifungal activity, especially against Trichophyton rubrum.

  • Isoimperatorin: Promotes blood circulation and skin absorption of active components, improving overall efficacy[8].

Benefits

With diverse biological activities, it is widely used in multiple fields, with core benefits:

Skin Health Benefits

Antibacterial and antifungal, supports comfort and skin balance, reduces irritation, improves skin barrier, suitable for sensitive skin[9].

Reproductive Health Benefits

Warms the kidney and invigorates yang, improves male sexual dysfunction; relieves female vaginal discomfort and inflammation. Osthole helps maintain healthy sexual function[7].

Anti-inflammatory & Antibacterial Benefits

Inhibits inflammatory factors, has broad-spectrum antibacterial effects, mild and free of obvious side effects, suitable for topical inflammation and microbial infections[9].

Other Benefits

Neuroprotective and osteogenic, prevents osteoporosis; antioxidant, scavenges free radicals, suitable for skin wellness support health products[8].

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Technical Specifications

ParameterValueMethod
ItemSpecificationTest Method
Product NameCnidium Monnieri ExtractVisual Identification
Botanical SourceFruits of _Cnidium monnieri (L.) Cuss._Pharmacopoeia Standard
Active Component ContentOsthole: 10% – 98% (Customizable); Ratio Extract: 10:1, 20:1, 30:1HPLC (Osthole); TLC (Ratio Extract)
Appearance10%-70%: Brownish-yellow to yellowish-green powder; 80%-98%: Light yellow to white crystalline powderOrganoleptic
Particle Size100% pass 80 meshSieve Method
Loss on Drying≤ 8.0%USP 36 <731>
Total Ash≤ 5.0%USP 36 <281>
Heavy MetalsPb ≤ 2 ppm; Cd ≤ 2 ppm; As ≤ 1 ppm; Hg ≤ 0.1 ppmAtomic Absorption Spectrometry
Microbial LimitsTotal Aerobic Bacteria ≤ 1000 CFU/g; Yeast & Mold ≤ 100 CFU/g; Coliforms/Salmonella: NegativeUSP 36 <61> <62>
Solvent ResidueEthanol ≤ 500 ppm; No other organic residuesGC
Pesticide ResidueMeet cosmetic and pharmaceutical standardsGC-MS
Shelf Life24-36 months (proper storage)Stability Test

Full batch-specific COA available on request.

Commercial Terms

MOQ
1 kg
Lead time
7-15 business days
Shelf life
24个月(按要求储存)
Sample
On request
Packaging
25kg/纸板桶;按客户要求包装
Storage
密闭,阴凉,防潮,避光。