Product Overview
Gingerol extract is a collective term for phenolic active ingredients derived from the rhizomes of Zingiber officinale (ginger), a well-known medicinal and edible herb. It is the primary source of ginger’s characteristic pungent taste and its major bioactive components. Among its constituents, [6]-gingerol is the most abundant and pharmacologically active compound, accounting for approximately 70% of total gingerols.
Active Ingredients
- [6]-Gingerol
- [8]-Gingerol
- [10]-Gingerol
- Shogaols, zingerone and related derivatives
Physicochemical Properties
Taking [6]-gingerol as the representative component:
- Molecular formula: C₁₇H₂₆O₄
- Molecular weight: 294.39
- Solubility: Soluble in ethanol, ethyl acetate, ether and other organic solvents
- Stability: Sensitive to heat and light; recommended to be stored sealed, away from light and at low temperatures
Key Benefits & Mechanisms
- Anti-inflammatory & Analgesic
Inhibits COX-2, NF-κB and other inflammatory pathways, relieves osteoarthritis, menstrual cramps and muscle soreness, and reduces inflammatory responses.
- Anti-emetic Effect
Regulates gastrointestinal motility and antagonizes 5-HT₃ receptors, helping relieve motion sickness, morning sickness and -induced nausea and vomiting.
- Digestive Support
Stimulates gastric juice secretion, enhances intestinal peristalsis, protects gastric mucosa, and improves abdominal distension and poor appetite.
- Antioxidant Activity
Scavenges free radicals, enhances the activity of antioxidant enzymes (e.g., glutathione peroxidase), and reduces oxidative stress damage.
- Cardiovascular Support
Promotes nitric oxide production, improves endothelial function, supports healthy blood lipid levels, and provides mild anti-platelet aggregation effects.
- Metabolic Regulation
Activates brown adipose tissue, increases basal metabolic rate, and assists in fat metabolism.
- Antimicrobial & Cosmetic Applications
Inhibits Escherichia coli, Staphylococcus aureus and other pathogens; promotes scalp blood circulation and supports hair health.
Main Applications
- Pharmaceutical & Nutraceuticals: Used in formulations for anti-inflammation, anti-emesis, digestion support and joint health supplements.
- Food Industry: Applied as a natural flavoring agent, preservative and functional ingredient in beverages, seasonings and snacks.
- Cosmetics & Personal Care: Added to skin care products for skin wellness support and brightening; used in hair care products to prevent hair loss and relieve dandruff.
Safety & Precautions
- Recommended Dosage: Daily dietary intake of 1–3 g of ginger (equivalent to 100–300 mg of gingerol) is safe. Supplemental intake is generally recommended not to exceed 1500 mg per day.
- Adverse Reactions: High doses (>6 g/day of raw ginger) may cause gastrointestinal discomfort, heartburn or diarrhea.
- Cautions:
- Not recommended for individuals with bleeding disorders or those taking anticoagulant medications.
- Use with caution in patients with gallstones, gastric ulcers, pregnant or lactating women.
Extraction & Quality Control
- Extraction Methods: Ethanol extraction, ultrasonic/microwave-assisted extraction, supercritical CO₂ extraction.
- Quality Testing: [6]-gingerol content quantified by HPLC; compliance with heavy metal limits (Pb ≤5 mg/kg, As ≤2 mg/kg) and microbial specifications for food and pharmaceutical grade materials.
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
