Introduction of Piperine
Piperine, the primary bioactive alkaloid in black pepper (Piper nigrum L.) and long pepper (Piper longum L.), is a natural extract widely used in nutraceutical, pharmaceutical, food, and cosmetic industries for its bioavailability-enhancing and multifunctional properties. Our Piperine is derived from high-quality Piper nigrum L. fruits from certified plantations in Sarawak, Malaysia, known for high piperine content and superior quality.
We adopt two advanced extraction processes: supercritical CO₂ extraction (zero solvent residue, high bioactivity) and food-grade ethanol extraction (cost-effective, large-scale production), both ensuring product purity.
Our Piperine offers customizable specifications (20%-98% piperine content, standard grades 95%/98% by HPLC), meeting strict industry requirements.
Differentiated advantages: premium raw materials with strict pre-testing, dual GMP/ISO-compliant extraction technologies, and high-purity, additive-free products that meet clean-label and GRAS standards.
Key Active Compounds
The core active compound is Piperine (CAS No.: 94-62-2), with molecular formula C₁₇H₁₉NO₃ and molecular weight 285.34 g·mol⁻¹. Its benzodioxole ring and piperidine group are key to its physiological activities.
Trace synergistic compounds (piperettine, piperlongumine, etc.) from Piper nigrum L. enhance piperine’s effects without harmful impurities, ensuring naturalness and safety.
Benefits
Piperine has well-documented physiological benefits, widely applicable in multiple fields:
- Bioavailability Enhancement: Inhibits liver/intestinal metabolic enzymes and P-glycoprotein efflux, significantly improving absorption of fat-soluble nutrients, drugs, and bioactive compounds (e.g., curcumin).
- Anti-inflammatory & Antioxidant Effects: Inhibits pro-inflammatory cytokines, scavenges free radicals, enhances SOD activity, and protects cells from oxidative damage.
- Metabolic & Weight Management Support: supports healthy metabolism, promotes thermogenesis and fat oxidation, and helps improve metabolic balance.
- Immune Regulation: Increases glutathione content, regulates immune cell function, and enhances body resistance.
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
