GreeneryBio
Rutin

Rutin

Product Name: Sophora japonica extract Synonym Name: Rutin Latin Origin: Sophora japonica L

Chemical identity

Appearance
Yellow fine powder Certification: ISO/HACCP/HALAL/KOSHER ## Introduction
MOQ
1 kg
Lead Time
7-15 business days

Certifications

ISO 9001ISO 22000

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Product Description

Introduction

Botanical Source & Raw Material Quality

Our Rutin is exclusively extracted from Sophora japonica L. (Japanese Pagoda Tree) buds, a time-honored botanical source renowned for its exceptional rutin concentration (23-25% in dried buds). We maintain strict sourcing protocols, partnering with GAP-certified plantations in China and Korea that practice sustainable cultivation without pesticides or chemical fertilizers. This ensures a consistent, high-quality raw material base that meets global organic standards.

Advanced Extraction & Purification Process

We employ a proprietary alkali extraction-acid precipitation combined with membrane separation technology, optimized for maximum rutin retention and purity:

  1. Pre-treatment: Raw buds undergo low-temperature drying and micro-pulverization to preserve bioactivity
  2. Extraction: pH-controlled alkaline solution extraction at 60-70°C with ultrasonic assistance to enhance yield by 25%
  3. Purification: Multi-stage filtration (microfiltration + ultrafiltration) removes plant fibers, proteins, and colloids
  4. Precipitation: Acidification under precise temperature control (5-10°C) to form pure rutin crystals
  5. Drying: Vacuum freeze-drying to maintain structural integrity and prevent thermal degradation
  6. Quality Assurance: HPLC fingerprinting throughout the process ensures batch-to-batch consistency

Potency & Standardization

Our Rutin is standardized to ≥95% purity (HPLC), with premium grades available at 98% and 99% purity. Each batch undergoes rigorous testing to confirm active compound concentration, ensuring compliance with NF11, USP43, and EP9 pharmacopeial standards.

Unique Differentiation Advantages

  • Superior Bioavailability: Specially formulated microcrystalline particles (D90 ≤ 10μm) enhance dissolution rate by 40% compared to conventional rutin
  • Low Impurity Profile: Total heavy metals <10ppm, residual solvents <500ppm, and microbiological counts meeting pharmaceutical-grade requirements
  • Sustainability Commitment: 100% renewable energy-powered production and zero-waste water treatment systems
  • Traceability: Blockchain-enabled supply chain tracking from seed to finished product
  • Customization: Tailored particle size, solubility, and formulation options (powder, granule, or liquid) to meet specific application needs

Key Active Compounds

Compound Chemical Formula Molecular Weight Content CAS Number
Rutin (Quercetin-3-rutinoside) C₂₇H₃₀O₁₆ 610.52 g/mol ≥95% 153-18-4
Quercetin (minor metabolite) C₁₅H₁₀O₇ 302.23 g/mol ≤2% 117-39-5
Isoquercitrin C₂₁H₂₀O₁₂ 464.38 g/mol ≤1% 482-35-9
Kaempferol glycosides C₂₇H₃₀O₁₅ 594.52 g/mol ≤0.5% N/A

Our Rutin is characterized by its high quercetin-3-rutinoside specificity (>98% of total flavonoids), distinguishing it from lower-grade products containing significant amounts of other flavonoid derivatives. The presence of minor quercetin metabolites enhances synergistic biological activity while maintaining product purity.

Benefits

Cardiovascular Health Support

Powerful Antioxidant & Anti-Inflammatory Effects

Metabolic & Immune Support

Physical & Chemical Properties

Parameter Specification Test Method
Appearance Yellow to greenish-yellow crystalline powder Visual inspection
Odor Characteristic, slightly aromatic Olfactory test
Melting Point 195-205°C (decomposition) DSC
Solubility Slightly soluble in water (0.125g/L at 20°C), soluble in methanol and alkaline solutions Solubility test
Loss on Drying ≤8.0% USP <731>
Ash Content ≤0.5% USP <281>
Particle Size D90 ≤ 10μm (standard grade), customizable Laser diffraction
pH (1% solution) 5.0-7.0 pH meter

Assay & Purity

Parameter Specification Test Method
Rutin Content ≥95.0% (98%/99% grades available) HPLC (USP <621>)
Quercetin ≤2.0% HPLC
Total Flavonoids ≥98.0% UV spectrophotometry
Heavy Metals Pb <2ppm, Cd <1ppm, As <1ppm, Hg <0.1ppm ICP-MS
Residual Solvents ≤500ppm GC-MS
Microbiological Limits Total Aerobic Count <1,000cfu/g, Yeast/Mold <100cfu/g, E. coli absent, Salmonella absent USP <61>/<62>

Packaging & Storage

  • Packaging: 1kg aluminum foil bags, 25kg fiber drums with double plastic liners
  • Shelf Life: 36 months from manufacturing date when stored properly
  • Storage Conditions: Store in a cool (15-25°C), dry place, protected from light and moisture

Application Cases

Pharmaceutical Industry

  1. Vascular Health Formulations:

  2. Anti-Diabetic Complications:

Nutraceutical & Functional Foods

  1. Cardiovascular Supplements:

  2. Sports Nutrition:

Cosmetics & Personal Care

  1. skin wellness support Serums:

  2. Sunscreen Formulations:

Food & Beverage Industry

  1. Functional Beverages:

  2. Bakery Products:

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Commercial Terms

MOQ
1 kg
Lead time
7-15 business days
Shelf life
24 months unopened
Sample
On request
Packaging
1 kg aluminum foil bag · 25 kg fiber drum
Storage
Sealed, cool, dry, light-protected